Sex Steroid Actions on Epiphyseal Maturation: Evolving New Concepts
نویسندگان
چکیده
منابع مشابه
Non-genomic actions of sex steroid hormones.
Steroid hormone receptors have been traditionally considered to act via the regulation of transcriptional processes, involving nuclear translocation and binding to specific response elements, and ultimately leading to regulation of gene expression. However, novel non-transcriptional mechanisms of signal transduction through steroid hormone receptors have been identified. These so-called 'non-ge...
متن کاملProtective actions of sex steroid hormones in Alzheimer's disease.
Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid hormones in both women and men. In post-menopausal women, the precipitous depletion of estrogens and progestogens is hypothesized to increase susceptibility to AD pathogenesis, a concept largely supported by epidemiological evidence but refuted by some clinical findings. Experimental evidence suggests that estr...
متن کاملFurther concepts on regulators of the sex ratio in human offspring. Non-optimal maturation of oocytes and the sex ratio.
Introduction In a prospective analysis on women who had discontinued contraception to start pregnancy, Weinberg et al. (1995) uncovered new data on the notion of why some conceptions result in boys, while others result in girls. The length of the follicular phase (from the onset of the menses to ovulation) was found to be related to the sex of the baby in 133 pregnancies that survived to delive...
متن کاملAtrial Remodeling: Evolving Concepts
The term "Electrophysiological remodeling" defines the changes of atrial electrophysiologic properties taking place in atrial myocites during atrial fibrillation and/or following periods of sustained atrial fibrillation (AF). Early research was prompted by clinical observations: many patients were seen to get through increasingly frequent and longer paroxisms of AF to persistent AF, until chron...
متن کاملNew and evolving concepts in the neurotoxicology of lead.
Lead (Pb) is a xenobiotic metal with no known essential function in cellular growth, proliferation, or signaling. Decades of research characterizing the toxicology of Pb have shown it to be a potent neurotoxicant, especially during nervous system development. New concepts in the neurotoxicology of Pb include advances in understanding the mechanisms and cellular specificity of Pb. Experimental s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Pediatric Endocrinology
سال: 1997
ISSN: 0918-5739,1347-7358
DOI: 10.1297/cpe.6.supple9_1